Revolutionizing Immunity – Optimizing CAR-T for Breakthrough Therapies
ABOUT US
CAR that unlocks the full potential of T-cells
We are driving the evolution of next-generation CAR-T cell therapy with precision-engineered CAR constructs. Our CAR discovery engine focuses on optimizing the binding domain of CAR to enhance immune cell function, delivering robust therapeutic efficacy. Optieum is pushing the boundaries of solid tumor treatment powered by next-generation CAR constructs.
SCIENCE
CAR Discovery Engine – Eumbody System
Our core platform technology utilizes empirical methodologies to identify optimized CAR, accelerating the development of advanced CAR-T cell therapies.
Through our novel approach, our CAR discovery process dynamically harmonizes scFv sequences via empirical evaluation, significantly enhancing the functional capabilities of T cells.
T-cells are a crucial part of the immune system, which require a certain level of signals to be activated. Identifying the precise level of stimulation that triggers T-cells to become fully and appropriately active is important in both immunology and therapeutic approaches like CAR-T cell therapy.
Our next-generation CAR constructs are engineered to achieve the optimal activation threshold for T-cells to ensure precise and efficient immune responses, demonstrating superior proliferative capacity, preventing antigen escape, and exhibiting exceptional reactivity against advanced tumor profiles.
OUR PIPELINE
PROGRAM-1FAPa
Discovery
Pre-Clinical
Phase 1
INDICATIONS
solid tumor, cancer associated fibroblast
PROGRAM-2CD19
Discovery
Pre-Clinical
Phase 1
INDICATIONS
hematological malignancies, autoimmune disorders
PROGRAM-3Discovery
Discovery
Pre-Clinical
Phase 1
INDICATIONS
Undisclosed
OUR TEAM
Leadership
Board of Directors
NEWS
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2022.12.13Announcement of Research License and Option Agreement with GI CELL
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2022.12.1Optieum Biotechnologies and National Cancer Center Japan Signed Joint Research Agreement on Solid Tumor Targeting CAR-T Cell Programs
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2022.1.27Announcement of Grant Award from NEDO
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2021.9.30Optieum Biotechnologies Raises JPY 290 million ($ 2.6 million) in Seed Round